A novel view on Alzheimer’s disease pathogenesis: modern conceptof amyloid clearance
نویسندگان
چکیده
منابع مشابه
Alzheimers Disease: A Novel Hypothesis for the Development and the Subsequent Role of Beta Amyloid
Spirochetes, biofilms, and innate immune system activity have all been recently found in the brains of Alzheimer’s disease patients. The mechanism and actions of those factors in producing the disease were discussed in those studies. However, neither the production nor the role of beta amyloid was included in the discussion of those studies. In this commentary, we hypothesize how the developmen...
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Objective(s): Increasing evidence suggests that Alzheimer’s disease (AD) is associated with diabetes. Rosiglitazone, a peroxisome proliferator-activated receptor γ (PPAR-γ) agonist and anti-diabetic agent, may improve symptoms of AD. However, the underlying therapeutic potential of it has not been fully elucidated. Materials and Methods: Rats were divided into four groups: control group, sham o...
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Since its first description in 1932, Crohn’s disease (CD) remains a challenging pathology. While still incurable, major improvements in medical and surgical treatments have been recently made. However, during their lifetime, up to 80% of patients with CD will eventually require surgery. Therefore, improving the outcomes is a major goal, but it requires a multidisciplinary environment. The aim o...
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Alzheimer’s disease (AD) is the most common form of dementia and is exacting a tremendous economic and personal toll on nations as well as families throughout the world and this toll will continue to grow over the passing decades. This crisis is compounded by the lack of effective treatments for this disease and the widespread failure of a multitude of therapeutic clinical trials targeting many...
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ژورنال
عنوان ژورنال: V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY
سال: 2018
ISSN: 2313-7053
DOI: 10.31363/2313-7053-2018-2-22-28